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Journal: Cancer Science
Article Title: Identification of circular RNAs as novel biomarkers and potentially functional competing endogenous RNA network for myelodysplastic syndrome patients
doi: 10.1111/cas.14843
Figure Lengend Snippet: Results of the sequence analysis of microRNA response elements (MREs) in patients with myelodysplastic syndrome. The 2D structure shows the MRE sequence, the target miRNA seed type, and the 3′ pairing sequence. Local AU shows the AU content 30 nt upstream and downstream of the seed sequences. The position column shows the most likely relative MRE position on the linear presentation of circular RNAs (circRNAs). A, Binding sites of hsa_circRNA_100352 targeting has‐miR‐627‐3p, has‐miR‐329‐5p, has‐miR‐25‐3p, has‐miR‐766‐5p, and has‐miR‐143‐5p predicted by TargetScan and miRanda. B, Binding sites of hsa_circRNA_104056 targeting has‐miR‐637, has‐miR‐623, has‐miR‐377‐3p, has‐miR‐193b‐5p, and has‐miR‐616‐3p predicted by TargetScan and miRanda. C, Binding sites of hsa_circRNA_102817 targeting has‐miR‐331‐5p, has‐miR‐298, has‐miR‐296‐3p, has‐miR‐30c‐1‐3p, and has‐miR‐588 predicted by TargetScan and miRanda
Article Snippet:
Techniques: Sequencing, Binding Assay